I would say the lion’s share of Breast Reconstruction today involves the placement of tissue expanders, followed by their removal and the replacement of permanent prosthesis. Since these expanders are placed under the muscle the amount of expansion can be limited due the tension and pain experienced by patients undergoing expansion.
A recent study of 30 patients was done with 15 patients receiving 40 units of Botox in 4 injection sites and 15 patients receiving saline injections. Those patients receiving Botox had less pain associated with their injections and also they had greater volumes injected at each sitting. Also after 7 days the rise of narcotics was less in the group receiving Botox.